Anticodon binding domain (EQ)

The anticodon binding domain EQ is a $\beta$-barrel structure. It resides at the C-termini of [GlnRS](/class1/gln/), [GluRS-E](/class1/glu3), and [GlxRS-A](/class1/glu2). The domain is distinct from the helical anticodon binding domain of the closely-related bacterial-like enzymes [GluRS-B](/class1/glu1) and GlxRS-B.

References

Hadd, Andrew, and John J. Perona. "Coevolution of specificity determinants in eukaryotic glutamyl-and glutaminyl-tRNA synthetases." Journal of molecular biology 426.21 (2014): 3619-3633.